Antithrombotic Therapy for Venous Thromboembolic Disease.

I t has been recognized for more than a century that For venous thrombosis, stasis and local alterations in stasis of blood, abnormalities of the vessel wall, blood elements are most important, since major and changes in the soluble and formed elements of pathologic changes are not seen routinely in the vessel the blood are the major contributors to thrombosis. wall at the nidus of a venous thrombus. Reprint requests: Dr. Hyers, Znternul Medicine (hlmonology), St. Antithrombotic regimens are available that modlfy ~ o u i . Uniuersity, 3635 Vita Awnue, st. h i . % ~ i s s w r i 63110 one or more of these abnormalities. These modalities